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You need two board wipes to answer it

Otherwise, this card could see competitive play, but Virtue of Knowledge really is tuned for the Commander format first and foremost

For almost all decks, the answer is no

You can't count on the Archangel actually connecting with lifelink through combat as she's one of the only targets for the removal spells your opponent has had in their hand all game

You can play whatever color you like or choose the creature type to get the benefit

Each of the cards was illustrated by an LGBTQIA2S+ artist, and will come in an exclusive rainbow foil box rather than the usual black ones Secret Lairs are delivered in